QWhat is a promoter and what does it do?

What is a promoter and what does it do?

AExpert Answer

 A promoter is the main regulatory portion of a gene.  The simplest analogy is that a promoter is a “switch” that turns a gene “on” or “off.” It is the portion of the gene where cellular machinery binds before transcribing the DNA blueprint into a useful RNA.  There are different types of RNA that may be transcribed, including messenger RNA’s (mRNAs) that encode useful proteins and regulatory RNAs that mediate gene silencing.  But, the first step is always binding of an RNA polymerase to the gene’s promoter.  No promoter, no useful RNAs or proteins!

 

In making transgenic plants, the gene of interest inserted into a plant genome must include a promoter to allow this gene to be switched “on” or transcribed.  One of the most common promoters used in engineering GM crops is the CaMV (Cauliflower Mosaic Virus) or “35S”promoter, which is a type of constitutive promoter (always “on”).  Different types of promoters, including those that require specific environmental signals in order to switch “on”, are found throughout the natural world. 

 

Recent Forbes article by David Kroll on the safety of the CaMV 35S promoter:

http://www.forbes.com/sites/davidkroll/2013/02/06/a-combination-of-unusual-rare-to-impossible-events-would-be-required-for-the-camv-35s-dna-sequence-to-be-a-human-health-risk/

Posted on June 28, 2017
The short answer is no, neither MSG or animal extraction are from GMOs, nor is MSG, animal extraction, or animal products/animal DNA in GMOs.   When people refer to Genetically Modified Organisms (GMOs), they are referring to precision plant breeding using genetic engineering (also called GE). It allows plant breeders to take a desirable trait (like resistance to drought, insects, weeds, and disease) from one plant or organism and transfer it to the plant... Read More
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Posted on June 28, 2017
No. MSG, monosodium glutamate, is a chemical additive, certainly not a GMO.
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Posted on June 28, 2017
Monosodium glutamate is mainly produced by a fermentation process with sugar as a starting material. It is not GMO. Plants that have been genetically modified do not contain any animal residue or byproducts.
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