GMOsux's picture
Does Monsanto crops or products contain the Epicyte gene or any other gene that acts in the same way to create antibodies that kill or block sperm?

A:Expert Answer

No, none of our products has ever contained gene encoding for anti-sperm antibodies.  To answer your specific question about Epicyte: we did not have any agreements with Epicyte or Biolex Therapeutics (the company that acquired Epicyte in 2004) to conduct joint research or develop products.  Claims that Monsanto was involved in the research or development of food crops containing antibodies that kill or block sperm are incorrect. 

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Comments

GMO Free America's picture

That's a good question. I too would like to learn more about the Epicyte Gene. Monsanto GM Crops are created with Glyphosate resistance or immunity. Glyphosate is an active ingredient of the most widely used Monsanto herbicide. Glyphosate, the active ingredient in Roundup.® "The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate's inhibition of cytochrome P450 (CYP) enzymes is an overlooked component of its toxicity to mammals. CYP enzymes play crucial roles in biology, one of which is to detoxify xenobiotics. Thus, GLYPHOSATE ENHANCED THE DAMAGING EFFECTS OF OTHER FOOD BORN CHEMICAL RESIDUES AND ENVIRONMENTAL TOXINS. Negative impact on the body is insidious and manifests slowly over time as inflammation damages cellular systems throughout the body...Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease. We explain THE DOCUMENTED EFFECTS OF GLYPHOSATE AND ITS ABILITY TO INDUCE DISEASE, and we show that glyphosate is the “textbook example” of exogenous semiotic entropy: the disruption of homeostasis by environmental toxins."(http://www.mdpi.com/1099-4300/15/4/1416)

Glyphosate induces human breast cancer cells growth via estrogen receptors (http://www.ncbi.nlm.nih.gov/pubmed/23756170)

So it seems that any reasonable person, agency or committee would seek to LIMIT or MINIMIZE the use and/or any "acceptable limits" of Glyphosate in the nations food supply RIGHT? Wrong: "EPA Raised Residue Limits of Monsanto’s Toxic Chemical Glyphosate Herbicide (http://www.motherearthnews.com/nature-and-environment/monsanto-glyphosat...)

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GMO Free America's picture

"Groundbreaking investigation reveals Monsanto teaming up with US military to target GMO activists" The report, which recently appeared in the July 13 print edition of Suddeutsche Zeitung (SZ), explains in rigorous detail how both individuals and groups opposed to GMOs and other chemical-based crop technologies have been threatened, hacked, slandered and terrorized for daring to digress from the pro-GMO status quo. On numerous documented occasions, pertinent information about the dangers of GMOs or lack of GMO safety data has been effectively blocked from timely release by mysterious forces that many say are the chemical industry in disguise. (http://www.naturalnews.com/041396_Monsanto_GMOs_US_government.html)

Cornlover's picture

Try to stay on topic

Goodfood's picture

I agree, the second comment is off topic but I would really like to hear some dialogue addressing the information in GMO Free America's first post.

pinkpetal's picture

How much longer will we deny the growing body of research linking Roundup to infertility before calling this chemical a contraceptive?

A new study published in the journal Free Radical Medicine & Biology implicates the herbicide, and its main ingredient glyphosate, in male infertility, at concentration ranges well within the EPA’s “safe level” for food.[1]

http://wakeup-world.com/2013/07/31/is-it-time-to-acknowledge-roundup-her...

GMO Free America's picture

Also...

*In 2005, Richard et al(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257596/). reported that “glyphosate is TOXIC TO HUMAN PLACENTAL JEG3 CELLS within 18 hr with concentrations lower than those found with agricultural use, and this effect increases with concentration and time or in the presence of Roundup adjuvants. Surprisingly, Roundup is always more toxic than its active ingredient. ... We conclude that endocrine and toxic effects of Roundup, not just glyphosate, can be observed in mammals.”
*In 2012, Mesnage et al(http://www.sciencedirect.com/science/article/pii/S0300483X12003459). reported, “This study demonstrates that all the glyphosate-based herbicides tested are more toxic than glyphosate alone ... The formulated herbicides (including Roundup) CAN AFFECT ALL LIVING CELLS, ESPECIALLY HUMAN CELLS. Among them, POE-15 clearly appears to be the most toxic principle against human cells, ... We demonstrate in addition that POE-15 induces necrosis when its first micellization process occurs, by contrast to glyphosate which is known to promote endocrine disrupting effects after entering cells.”' (See Graphs & Charts on pp. 8-14)
*Mounting evidence that GMO crops can cause INFERTILITY AND BIRTH DEFECTS The endocrine disrupting properties of glyphosate can lead to reproductive problems: INFERTILITY, MISCARRIAGE, BIRTH DEFECTS, AND SEXUAL DEVELOPMENT (see notes). FETUSES, INFANTS AND CHILDREN ARE ESPECIALLY SUSCEPTIBLE because they are continually experiencing growth and hormonal changes...There are increasing reports of glyphosates and glyphosate formulations causing SEXUAL DYSFUNCTION, LOW BIRTH WEIGHT, FEWER BIRTHS AND STERILITY IN LAGABORTORY ANIMALS, FARM ANIMALS AND HUMANS (see notes).
*A Russian study found that feeding hamsters GMO soy resulted in COMPLETE STERILITY AFTER TWO OR THREE GENERATIONS (http://english.ruvr.ru/2010/04/16/6524765.html/). (pg. 16)
NOTES:
*INFERTILITY AND LOW BIRTH RATES:
*Laboratory animals: In 1995 Yousef et al(http://www.ncbi.nlm.nih.gov/pubmed/7797819). reported on toxic effects of glyphosate on semen characteristics in rabbits, “Pesticide treatment resulted in a DECLINE IN BODY WEIGHT, LIBIDO, EJACULATE VOLUME, SPERM CONCENTRATION, SEMEN INITIAL FRUCTOSE AND SEMEN OSMOLALITY. This was accompanied with increases in the ABNORMAL AND DEAD SPERM.”
*In 2002 Markaverich et al (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240732/). found that, “Housing adult rats on ground corncob bedding IMPEDES MALE AND FEMALE MATING BEHAVIOR and CAUSES ACYCLICITY IN FEMALES [not according to regular cycles].”
*In 2008, Austrian researchers found that mice fed GM corn produced FEWER AND SMALLER BABIES than those fed a non-GM diet (http://www.biosicherheit.de/pdf/aktuell/zentek_studie_2008.pdf).
*In April 2010, a Russian study (http://english.ruvr.ru/2010/04/16/6524765.html/)found that after feeding hamsters GM soy for two years over three generations, most were STERILE BY THE THIRD GENERATION.
*2011 Siepmann et al(http://www.ncbi.nlm.nih.gov/pubmed/21353476). reported, “HYPOGONADISM [functional incompetence of the gonads especially in the male with subnormal or impaired production of hormones and germ cells] and ERECTILE DYSFUNCTION associated with soy product
*In 2012 Antoniou et al(http://people.csail.mit.edu/seneff/glyphosate/NancySwanson.pdf). published a review of the evidence of the reproductive toxicity of glyphosate herbicides and concluded that a new and transparent risk assessment needs to be conducted.
*In 2012 Irina Ermakova (http://www.regnum.ru/english/526651.html)reported low birth weight and a 55.6% mortality rate in the babies of rats fed GMO soy compared to 6.8% in the control group.
FARM ANIMALS:
*An Iowa pig farmer reports sterility and false pregnancies in pigs fed GMO corn (http://gaia-health.com/gaia-blog/2012-01-23/former-agribusiness-farmer-l...).
*A Danish pig farmer reports birth defects, infertility and low birth rate in pigs fed GMO corn. (http://www.gmfreecymru.org/pivotal_papers/danish_dossier.html).
HUMANS:
*In 2001 Arbuckle et al, reported on the effect of pesticide exposure on the risk of SPONTANEOUS ABORTION.... (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240415/)
BIRTH DEFFECTS:
Cells:
*In 2005, Richard et al(Differential Effects of Glyphosate and Roundup on Human Placental Cells and Aromatase http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257596/). reported that “glyphosate is TOXIC TO HUMAN PLACENTAL JEG3 CELLS within 18 hr with concentrations lower than those found with agricultural use, and this effect increases with concentration and time or in the presence of Roundup adjuvants.”
*In 2009, Benachour et al (http://pubs.acs.org/doi/abs/10.1021/tx800218n). evaluated the toxicity of four glyphosate (G)-based herbicides in Roundup formulations on three different human cell types using a dilution far below agricultural recommendations and corresponds to low levels of residues in food or feed. They reported that glyphosate formulations induce APOPTOSIS [CELL SELF-DESTRUCTION] and NECROSIS [TISSUE DEATH IN HUMAN UMBILICAL, EMBRYONIC, AND PLACENTAL CELLS.
AMPHIBIANS:
In 2010, Paganelli et al(http://pubs.acs.org/doi/abs/10.1021/tx1001749). injected low doses (lower than levels used in fumigating) of glyphosate into AMPHIBIAN EMBRYOS and recorded BRAINS, INTESTINAL AND HEART DEFECTS IN THE FETUSES. Effects included REDUCED HEAD SIZE, GENETIC ALTERATION IN THE CENTRAL NERVOUS SYSTEM, INCREASED DEATH OF CELLS THAT HELP FORM THE SKULL, DEFORMED CARTLAGE, EYE DEFECTS, AND UNDEVELOPED KIDNEYS. In addition, the GLYPHOSATE WAS NOT BREAKING DOWN IN THE CELLS, BUT WAS ACCUMULATING. According to the authors THESE RESULTS ARE "COMPLETELY COMPARABLE TO WHAT WOULD HAPPEN IN THE DEVELPMENT OF THE HUMAN EMBRYO”
HUMANS:
*In 2009, Mesnage et al(http://oem.bmj.com/content/early/2009/11/30/oem.2009.052969.abstract). reported TWO CASES OF BIRTH DEFECTS in the same family in France after multiple pesticide exposure. “Many pesticides were used by this family around pregnancies. The father sprayed, without protection, more than 1.3 tons of pesticides per year including 300 liters of glyphosate based herbicides.”
In 2009, Winchester et al.(http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667895/), reported, “Elevated concentrations of agrichemicals in surface water in April–July coincided with HIGHER RISK OF BIRTH DEFECTS IN LIVE BIRTHS WITH LMPs [last menstrual periods] April–July.”
DATA SOURCES:
ART data: CDC (http://www.cdc.gov/art/ART2009/section5.htm)
Infant mortality data: CDC (http://www.cdc.gov/nchs/data_access/Vitalstatsonline.htm)
LBW and preterm birth data: CDC (http://205.207.175.93/Vitalstats/ReportFolders/reportFolders.aspx) and CDC Interactive tables (http://www.cdc.gov/nchs/data_access/vitalstats/VitalStats_Births.htm) (pp 17-20)
(via https://www.facebook.com/permalink.php?story_fbid=414122695363369&id=396... from "Genetically Modified Organisms and the deterioration of health in the United States N.L. Swanson, 4/24/2013"
(http://people.csail.mit.edu/seneff/glyphosate/NancySwanson.pdf) (Emphasis mine)

Community Manager's picture

Thanks for your comments @gmofreeamerica and @pinkpetal. We invite you to submit new questions which directly addresses these topics. Sticking to the subject makes conversational threads easier for others to follow.

Rickinreallife's picture

GMO Free America copied and pasted the abstract from the Sensel and Seneff paper published in Entropy entitled "Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases." I am not in any way a scientist nor have any specialized knowledge or training in the topic of the paper, so I am not able to competently address each of the claims. I am assuming the person who copied and pasted in the comment is not either, as the GMO Free America comment posts are almost entirely pasted passages of text from other sources. My only point is to dispute the inference of these posts, including the hypothesis that Samsel and Sneff propose regarding glysophate and a listing of chronic human illnesses, that there is widespread acceptance of the plausibility of Samsel and Senef's thoeories, or even that these theories were arrived at by thorough sensible interpretation and application of available literature. In fact, if there is any consensus, it appears to be that Samsel and Seneff's paper is faulty in many fatal respects.

Here are excerpts is one critique of their central thesis found here: "Is Glyphosate Poisoning Everyone?" [http://pipeline.corante.com/archives/2013/04/30/is_glyphosate_poisoning_...

". . . let's go right to the central thesis that glyphosate inhibits CYP enzymes in the liver. Here's a quote from the paper itself:
. . . "Glyphosate is an organophosphate. Inhibition of CYP enzyme activity in human hepatic cells is a well-established property of organophosphates commonly used as pesticides [121] -- (Note [121] is footnote citation to Abass, K "An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes".)

" What you wouldn't know from reading through all of it is that their reference 121 actually tested glyphosate against human CYP enzymes. In fact, you wouldn't know that anyone has ever actually done such an experiment, because all the evidence adduced in the paper is indirect - this species does that, so humans might do this, and this might be that, because this other thing over here has been shown that it could be something else. But the direct evidence is available, and is not cited - in fact, it's explicitly ignored. Reference 121 showed that glyphosate was inactive against all human CYP isoforms except 2C9, where it had in IC50 of 3.7 micromolar. You would also not know from this new paper that there is no way that ingested glyphosate could possibly reach levels in humans to inhibit CYP2C9 at that potency. "

Here is another passage from Samsel and Seneff: "Pseudomonas spp. is an opportunistic pathogen and an antibiotic-resistant Gram-negative bacterium that has been shown to be able to break down glyphosate to produce usable phosphate and carbon for amino acid synthesis, but a toxic by-product of the reaction is formaldehyde [37], which is neurotoxic, and low levels of formaldehyde can induce amyloid-like misfolding of tau protein in neurons, forming protein aggregates similar to those observed in association with Alzheimer's disease [38]." This hypothesis is dissected here: [http://www.biofortified.org/community/forum/genetic-engineering-group3/i...