Messing with nature is a very bad idea. Intervening in an intelligent, tested and proven way as we do with vaccines, medicines, controlled burns, creating natural parks, domesticating animals and creating new species of fruits and vegetables is what is required. Critics of GMO sometimes say we should not “play God”. But it is not the God part of the objection that worries me. We are not close to being smart enough or creative enough or even peaceful enough to engage that role. What we cannot have is “playing” or what you call "messing around." We need to closely regulate who can use GMO, when, where, why and with what penalties if they cause harms.