Kyle Scottke, Ph.D.
Molecular Analyst, Bayer Crop Science
Expert Bio
I am a molecular biologist with a background in plant molecular genetics and biochemistry. I earned my Ph.D. in Molecular Biology, Cell Biology, and Biochemistry from Brown University and my B.S. in Biotechnology from the Rochester Institute of Technology. My graduate work centered on understanding the molecular mechanism underlying Protein Phosphatase 2A regulation of ethylene biosynthesis in the model plant Arabidopsis. Since joining Monsanto in 2011, I have worked in Regulatory Science to characterize novel transgenic products at the molecular level. I am currently a Molecular Analyst at Bayer.
Studies, Articles and Answers
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Q: how are marker genes removed
A: Simply stated, a marker gene is removed or segregated away through traditional breeding. If you are interested in the scientific explanation, please keep reading. Marker genes are an extremely useful tool for generating transgenic (GMO) plants. Although there are several plant transformation methods and many types of marker genes, I will focus on one transformation method and class of marker gene in my answer. Agrobacterium-mediated transformation is one of the most commonly used plant transformation techniques and is used in basic biology research to develop transgenic plants. [...]
A: In plant biotechnology, marker genes, also frequently called “selectable markers,” are used to identify plants in which a transgenic trait has been successfully inserted. A good example of a selectable marker is herbicide resistance. In this case, the breeder sprays an herbicide on the plants of interest. Those that were not successfully transformed will be affected by the herbicide and discarded. Some marker genes can be both a marker gene and a commercial transgenic trait. In that situation, the marker is never removed. In other situations, markers are removed during th [...]
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